Water fluoridation, osteoporosis, fractures--recent developments.

نویسندگان

  • L L Demos
  • H Kazda
  • F M Cicuttini
  • M I Sinclair
  • C K Fairley
چکیده

BACKGROUND Optimal (1ppm) water fluoridation is seen as the most socially equitable way to prevent dental caries, however concerns about the safety of fluoridation are periodically raised. METHODS Research on effects on bone published since the 1991 National Health and Medical Research Council report on water fluoridation was reviewed. RESULTS Thirty-three studies were identified. Adverse effects in animal feeding studies were only seen at doses much greater than those currently used in artificial water fluoridation. The majority of animal studies showed no effect or a beneficial effect of low fluoride doses. The results of ecological studies were conflicting. One of the two cohort studies showed an increase in fracture incidence at fluoride levels four times greater than optimal water fluoridation and the other showed no effect after 20 years' optimal fluoridation. The cross-sectional studies showed a favourable effect on bone mineral density. The clinical trials predominantly showed increased bone density in several sites associated with fluoride treatment of 9-22.6mg fluoride per day for one-four years. CONCLUSION These studies provide a substantial body of evidence that fluoride at up to 1ppm does not have an adverse effect on bone strength, bone mineral density or fracture incidence.

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منابع مشابه

Why I changed my mind about water fluoridation.

46. Jacobsen SJ, O'Fallon WM, Melton III IJ. Hip fracture incidence before and after fluoridation of the publicwater supply, Rochester, Minnesota. American Journal of Public Health 83 743-745 1993.47. Suarez-Almazor ME, Flowerdew G, Saunders LD et al. The fluoridation of drinking water and hip fracturehospitalization rates in 2 Canadian communities. American Journal of Public He...

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Community water fluoridation, bone mineral density, and fractures: prospective study of effects in older women.

OBJECTIVE To determine whether fluoridation influences bone mineral density and fractures in older women. DESIGN Multicentre prospective study on risk factors for osteoporosis and fractures. SETTING Four community based centres in the United States. PARTICIPANTS 9704 ambulatory women without bilateral hip replacements enrolled during 1986-8; 7129 provided information on exposure to fluori...

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Op-phej120021 1..12

A recent decision by several Australian federal politicians to support a parliamentary review of artificial water fluoridation has an intensified debate on the public health intervention. While there is a majority agreement among Australian dentists and other health professionals that adequate enamel fluoride is essential for dental health, the ethics of artificial fluoridation of public water ...

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عنوان ژورنال:
  • Australian dental journal

دوره 46 2  شماره 

صفحات  -

تاریخ انتشار 2001